Effect of Music on Reading Comprehension for Patients With Aphasia "EMRA1"

Completed

Phase N/A Results N/A

Trial Description

This investigation uses a single-subject, adapted alternating research design to compare two different experimental conditions using music with lyrics combined with visual stimulation of the written lyrics, to extend the emotional word effect to phrases, in order to stimulate reading comprehension of the trained material for patients with aphasia. The two music conditions include 1) music with sung lyrics simultaneously with silent reading of the written lyrics; and 2) music with sung lyrics, followed by silent reading of the written lyrics (i.e. priming with the music). A control set without music will be used additionally within every third session to detect potential history and maturation effects. All conditions will be followed by a silent reading phrase-completion task composed of written words from the total combined sets of stimuli.

Detailed Description

The purpose of this investigation is to examine the evidence on emotion, language, and music, and propose a first step, in the form of a single-subject research design, to determine the most effective and efficient method for application to the rehabilitation of patients with aphasia. A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music. Risks are expected to be minimal. The risk is confidentiality. Risk management procedures in this study include: assuring confidentiality of participants, assuring qualified personnel, assuring convenient location, ensuring adequate enrollment, continual monitoring, addressing potential conflicts of interest, and making a plan to manage problems. Continual monitoring will be used to assess whether study interventions appear to be interfering with normal speech therapy treatment. If the researcher sees any signs of interference, the subject will be withdrawn from the research and study interventions will be stopped.

Conditions

Interventions

  • Control Other
    Intervention Desc: control condition using reading materials without music.
    ARM 1: Kind: Experimental
    Label: Music and reading lyrics
    Description: A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music.
  • Simultaneous music and reading lyrics Behavioral
    Intervention Desc: music with sung lyrics simultaneously with silent reading of the lyrics.
    ARM 1: Kind: Experimental
    Label: Music and reading lyrics
    Description: A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music.
  • Priming with music Behavioral
    Intervention Desc: priming with music and sung lyrics followed by reading of the lyrics.
    ARM 1: Kind: Experimental
    Label: Music and reading lyrics
    Description: A single-subject adapted alternating treatment design will be used to compare two music conditions, using music with sung lyrics simultaneously with silent reading of the lyrics, and priming with music and sung lyrics followed by reading of the lyrics, with a control condition using reading materials without music.

Trial Design

  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Percent correct responses per day on phrase completion task. through study completion, an average of 1 year No
Primary Number of sessions required to achieve mastery. through study completion, an average of 1 year No
Primary Retention of the reading material 3 weeks post-intervention. No
Secondary International Classification of Functioning, Disability, and Health (ICF) Body Functions/Structures, Activities, and Participation through study completion, an average of 1 year No
Secondary Boston Diagnostic Aphasia Examination (BDAE) through study completion, an average of 1 year No

Sponsors