Effect of Donepezil on the Reorganization of Cognitive Neural Network in Patients With Post-Stroke Cognitive Impairment


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Ischemic stroke in the territory of right or left middle cerebral artery
- Post-onset duration of the recent-onset stroke is over 3 months
- Cognitive deficit ranged from 10 to 26 by minimal mental status examination (MMSE) score
- Disturbance in activities of daily living (ADL) ranged 0.5 ~ 2.0 by clinical dementia rating (CDR) scale

Exclusion Criteria

- Severe internal carotid artery stenosis on the lesion side
- Cardiac pacemaker or intracranial metal insertion
- Post-stroke seizure disorder or any evidence of epileptic spikes on electroencephalography (EEG)