Effect of Combined Therapy on Neglect Syndrome in Stroke Patients

Completed

Phase N/A Results N/A

Trial Description

The purpose of the current study is to evaluate motor and neglect recovery of stroke patients produced by CIT using kinematic and oculomotor assessment, together with conventional clinical measures.

Detailed Description

This project will be carried out using a short term constraint and training protocol targeting at subacute and chronic patients with motor and perceptual deficits. The outcome measures will include kinematic and oculomotor analyses, which have not been employed yet.

Conditions

Interventions

  • Conventional therapy Other
    Intervention Desc: Traditional occupational therapy matched in intensity and duration with the other groups. The training program included stretching and weight bearing of the affected UE, improving the range of motion of the affected UE, muscle strengthening, and the practice of tasks used for functional training might involve the unaffected UE to assist in the affected UE; for example, stabilizing a bottle while opening its lid or moving pegs into holes on a board.
    ARM 1: Kind: Experimental
    Label: 3
    Description: conventional therapy
    ARM 2: Kind: Experimental
    Label: conventional therapy
    Description: traditional occupational therapy matched in intensity and duration with the other groups. The training program included stretching and weight bearing of the affected UE, improving the range of motion of the affected UE, muscle strengthening, and the practice of tasks used for functional training might involve the unaffected UE to assist in the affected UE; for example, stabilizing a bottle while opening its lid or moving pegs into holes on a board.
  • Constraint-induced therapy and eye-patching therapy(combined therapy)(CT) Other
    ARM 1: Kind: Experimental
    Label: 1
    Description: constraint-induced therapy and eye-patching therapy(combined therapy)
  • Constraint-induced therapy(CIT) Other
    ARM 1: Kind: Experimental
    Label: 2
    Description: constraint-induced therapy
  • EP Other
    Other Names: eye-patching therapy
    Intervention Desc: Participants were asked to wear glasses with a patch on the right lens to block the visual stimuli from the right side and force them to receive the stimuli from the left-side visual field.
    ARM 1: Kind: Experimental
    Label: CIT with eye-patching
    Description: The CIT addressed forced use of the affected UE and restricted the unaffected UE during training. Shaping skills were delivered while participants were forced to use their affected UE in the mass practice of functional tasks, such as drinking water and opening a jar. Participants wore a mitt on their unaffected hand and wrist for 6 hours/day during the 3-week training and reported their compliance in a daily log. Participants were also asked to wear glasses with a patch on the right lens to block the visual stimuli from the right side and force them to receive the stimuli from the left-side visual field.
  • CIT Other
    Other Names: constraint-induced therapy(CIT)
    Intervention Desc: The CIT addressed forced use of the affected UE and restricted the unaffected UE during training. Shaping skills were delivered while participants were forced to use their affected UE in the mass practice of functional tasks, such as drinking water and opening a jar. Participants wore a mitt on their unaffected hand and wrist for 6 hours/day during the 3-week training and reported their compliance in a daily log.
    ARM 1: Kind: Experimental
    Label: CIT with eye-patching
    Description: The CIT addressed forced use of the affected UE and restricted the unaffected UE during training. Shaping skills were delivered while participants were forced to use their affected UE in the mass practice of functional tasks, such as drinking water and opening a jar. Participants wore a mitt on their unaffected hand and wrist for 6 hours/day during the 3-week training and reported their compliance in a daily log. Participants were also asked to wear glasses with a patch on the right lens to block the visual stimuli from the right side and force them to receive the stimuli from the left-side visual field.
    ARM 2: Kind: Experimental
    Label: constraint-induced therapy
    Description: The intervention in this group resembled the intervention of the CIT+EP group, except participants did not wear the EP glasses.

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Kinematic and oculomotor assessment 2008-2009 Yes
Secondary Clinical measures at the impairment, activity, participation levels 2008-2009 Yes
Primary Catherine Bergego Scale (CBS) 2008-2009 No
Secondary Eye movement analysis 2008-2009 No
Secondary kinematic variables 2008-2009 No

Sponsors