Edaravone and Argatroban Stroke Therapy Study for Acute Ischemic Stroke "EAST"


Phase 4 Results

Summary of Purpose

Edaravone, a free radical scavenger, is a novel neuroprotective agent, and argatroban is a selective thrombin inhibitor. Both the drugs were approved by the Japanese Government, and have frequently been used for the treatment of acute brain infarction in Japan. The effect of combination therapy of these drugs, however, has not yet been elucidated. This study will test the safety and efficacy of the combination...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 12 May 2008.

1 Aug 2004 8 Sep 2005 1 Mar 2008 1 May 2008 1 May 2008 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


Not available