This study aimed to evaluate effectiveness of initial limb rehabilitation compare therapy took place within 48h with therapy took place after 48h for patients with stroke (modified Rankin Scale Score 3-4).
Early rehabilitation after stroke is thought to contribute to the effects of stroke-unit care. However, time of initial rehabilitation therapy is poorly defined and not underpinned by strong evidence in patients with stroke (modified Rankin Scale Score 3-4). The investigators do this parallel-group, single-blind, randomized controlled trial in shengjing hospital of China Medical University. Participants (aged≥18 years) with ischaemic or haemorrhagic stroke, first or recurrent, who meet physiological criteria are randomly assigned (1:1), to receive usual stroke therapy. Treatment with recombinant tissue plasminogen activator is allowed. Randomisation is stratified by study site and stroke severity. The primary outcome was a outcome 3 months after stroke, defined as a modified Rankin Scale score of 3-4. The investigators do analysis on an intention-to-treat basis.
- Initial Limb Rehabilitation Was Taken With Stroke Within 48h or After 48h Onset. The Limb Motor Performance Was Evaluated by Fugl-Meyer Score.
- Initial Limb Rehabilitation in Stroke Was Taken Within 48h Onset, or Taken After 48h Onset. Limb Motor Performance Was Evaluated by Fugl-Meyer Score.
- Limb Rehabilitation After Stroke is Studied.
- Time of First Rehabilitation Therapy
- Observation: Cohort
- Perspective: Prospective
- Sampling: Non-Probability Sample
Patients attacks acute stroke within 24h onset
|Type||Measure||Time Frame||Safety Issue|
|Primary||The primary outcome was a favourable outcome at 3 months after stroke, measured with the Fugl-Meyer motor function score.||90 days||No|
|Secondary||The primary outcome was a favourable outcome at 3 months after stroke, measured with Modified Rankin Scale score.||90 days|
- Shengjing Hospital Lead