Early Limb Rehabilitation Therapy Within 48 h of Acute Stroke Onset(ERTAS) "ERTAS"

Active, not recruiting

Phase N/A Results N/A

Trial Description

This study aimed to evaluate effectiveness of initial limb rehabilitation compare therapy took place within 48h with therapy took place after 48h for patients with stroke (modified Rankin Scale Score 3-4).

Detailed Description

Early rehabilitation after stroke is thought to contribute to the effects of stroke-unit care. However, time of initial rehabilitation therapy is poorly defined and not underpinned by strong evidence in patients with stroke (modified Rankin Scale Score 3-4). The investigators do this parallel-group, single-blind, randomized controlled trial in shengjing hospital of China Medical University. Participants (agedā‰„18 years) with ischaemic or haemorrhagic stroke, first or recurrent, who meet physiological criteria are randomly assigned (1:1), to receive usual stroke therapy. Treatment with recombinant tissue plasminogen activator is allowed. Randomisation is stratified by study site and stroke severity. The primary outcome was a outcome 3 months after stroke, defined as a modified Rankin Scale score of 3-4. The investigators do analysis on an intention-to-treat basis.

Conditions

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample

Trial Population

Patients attacks acute stroke within 24h onset

Outcomes

Type Measure Time Frame Safety Issue
Primary The primary outcome was a favourable outcome at 3 months after stroke, measured with the Fugl-Meyer motor function score. 90 days No
Secondary The primary outcome was a favourable outcome at 3 months after stroke, measured with Modified Rankin Scale score. 90 days

Sponsors