Dual antiplatelet therapy in the acute phase following stroke and transient ischaemic attack (TIA): which is the best regimen? "AMBDAP "

Completed

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. Women or men aged greater than 18 years 2. Patients with greater than or equal to 50% carotid artery stenosis 3. Symptoms of TIA or stroke within the last month 4. Baseline magnetic resonance imaging (MRI) or computed tomography (CT) imaging has been performed 5. Consented to take part in the study

Exclusion Criteria

1. Currently taking antiplatelet/antithrombotic medication other than aspirin (although low does prophylactic subcutaneous heparin for deep vein thrombosis [DVT] prophylaxis will be allowed) 2. Patients with prosthetic heart valves who have gaseous embolic signals 3. Where clopidogrel or dipyridamole is contra-indicated 4. Carotid endarterectomy planned within the next month 5. Pregnant and lactating women