Double-blind Randomized Trial of Intravenous Glycerol in Acute Stroke

Completed

Phase N/A Results

Trial Description

To evaluate the effects of intravenous glycerol.

Interventions

Trial Design

Double-blind randomized controlled trial of 173 patients.

Patient Involvement

Patients received either 500 ml of a 10% solution of glycerol in physiological saline or 500 ml of physiological saline administered intravenously over 4 h daily for 6 consecutive days.

Outcomes

Type Measure Time Frame Safety Issue
Primary Death, neurological and functional recovery of survivors as measured upon entry and after 3, 7, 21, and 84 days and 1 year. At 84 days and 1 year, length of hospital stay, and the proportion able to return to live in their own home were also assessed.