Donepezil Trial for Motor Recovery in Acute Stroke

Not yet recruiting

Phase 1/2 Results N/A

Summary of Purpose

Stroke is a major personal and social burden, being the commonest cause of severe adult disability. Recovery has been shown in animal models to be dependent upon adequate levels of acetylcholine within the brain - which in stroke is likely to be deficient. This is because acetylcholine-producing nerve cells in the brain are often damaged by strokes. Consequently, the investigators hypothesise that recovery may...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 29 September 2011.

1 Nov 2011 21 Sep 2011 1 Nov 2013 1 May 2014 1 Sep 2011 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Basics




Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


  • Paul Bentley, MA MRCP PhD