About one-third of patients with stroke have no documented cause for the cerebrovascular event (known as cryptogenic strokes). Atrial fibrillation is a common cause of stroke, but when transient (paroxysmal) it may remain undiagnosed. Recent data suggest that occult paroxysmal atrial fibrillation may be identified in patients with cryptogenic strokes using prolonged ambulatory cardiac rhythm monitors.
The investigators designed this study pursuing the following goals:
1. To determine the prevalence of occult paroxysmal atrial fibrillation in patients with cryptogenic stroke using long-term mobile cardiac outpatient telemetry.
2. To compare this prevalence to that found in a control group with stroke of known, non-cardioembolic cause.
3. To look for clinical, laboratory, echocardiographic, and imaging data that serve as risk factors for occult paroxysmal atrial fibrillation in patients with cryptogenic stroke.
4. To examine the utility of mobile cardiac outpatient telemetry, a relatively new diagnostic tool, in the evaluation of patients with cryptogenic stroke.
- Mobile cardiac rhythm monitoring Other
Intervention Desc: Continuous ambulatory cardiac rhythm monitoring using the CardioNet MCOT device ARM 1: Kind: Experimental Label: Cryptogenic stroke Description: Patients with stroke of unknown cause after comprehensive conventional evaluation ARM 2: Kind: Experimental Label: Stroke of known cause Description: Patients with stroke of known cause determined by comprehensive conventional evaluation
- Observation: Case Control
- Perspective: Prospective
- Sampling: Non-Probability Sample
Patients with stroke or TIA confirmed by a vascular neurologist within previous 3 months with complete evaluation for stroke causes according to current standards.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Detection of Atrial Fibrillation||21 days||No|
|Secondary||Time to first episode of atrial fibrillation||No|
|Secondary||Atrial Fibrillation Load||No|
|Secondary||Adverse events related to mobile cardiac monitoring||21 days||Yes|
|Secondary||Symptomatic status of episode of atrial fibrillation||21 days||No|
|Secondary||Longest duration of episode of atrial fibrillation||21 days||No|