Desmoteplase in Acute Ischemic Stroke (DIAS)


Phase 2 Results N/A

Summary of Purpose

The DIAS study (Part 2) was performed to support the dose finding of desmoteplase treatment in subjects with acute ischemic stroke selected by perfusion/diffusion mismatch on MRI within a time window of 3 to 9 h after stroke-symptom onset. In addition, it assessed safety and tolerability of 3 doses of desmoteplase compared with placebo with special consideration of intracranial hemorrhage and major systemic...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 12 March 2008.

1 Mar 2001 12 Mar 2008 1 Oct 2003 1 Oct 2003 1 Mar 2008 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Basics




Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


Not available