Decompressive surgery for the treatment of malignant infarction of the middle cerebral artery 2 "DESTINY-2"

Active, not recruiting

Phase N/A Results N/A

Summary of Purpose

In patients older than 60 years with space-occupying malignant supra-tentorial ischaemic infarcts, decompressive hemicraniectomy significantly decreases mortality or very severe disability, and improves disability, functional neurological deficit, and quality of life compared to conservative intensive care treatment.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 18 February 2010.

Unavailable Unavailable Unavailable Unavailable Unavailable Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Basics



  • German Research Council (Deutsche Forschungsgemeinschaft [DFG]) (Germany) (ref: JU 2764/1-1)

Trial Design

Prospective randomised open controlled multicentre phase III comparative trial.


Not available