Database for Stroke in Infants and Children

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

• A patient will be eligible for the study if s/he meets all of the following criteria for each stroke type:
AIS
- Age: term birth (gestation > 36 weeks) to 18 years of age
- Event diagnosed after January 1st, 2003
- Must have both clinical and radiological evidence present
1. Focal neurological deficit of acute onset lasting greater than 20 minutes. AND computed tomography (CT) or magnetic resonance imaging (MRI) showing infarct in location consistent with neurological signs and symptoms.
2. Neonates: seizures or lethargy alone may be the only acute symptom AND CT or MRI showing infarct.
3. Haemorrhagic infarction (ischemic infarct with secondary haemorrhage)
4. Hypoxic ischemic event with diffuse or bilateral infarction, if there is in addition a definite focal, single arterial infarct in a specified vascular territory. (e.g. middle cerebral artery, or MCA, mentioned in the radiographic report.)
CSVT
- Age: birth (premature infants included) to 18 years of age
- Event diagnosed after January 1st, 2003
- Must have both clinical and radiological evidence present
1. Clinical criteria: any transient neurological dysfunction including
- headache, seizure, decreased level of consciousness
- focal neurological signs consistent with CSVT
2. Neuroimaging criteria: thrombosis of cerebral veins or venous sinuses seen on MRI, MR venography, CT venography
Note: for older infants and children CT alone if definite is acceptable, but not for neonates under 1 month of age.
Cerebrovascular condition other than CSVT/AIS
1. Presumed pre/perinatal ischemic stroke (PPIS): infants and children whose stroke is presumed to have occurred in the prenatal or perinatal period. These patients have a normal developmental history up until about 4-8 months of age, when they present with early hand preference or hemiparesis. Neuroimaging shows an old infarct.
2. IPSS only apply the term TIA (Transient Ischemic Attack) to transitory (less than 24 hours) neurological deficit of vascular origin with no visible (new) infarct on neuroimaging.
3. Arteritis, vasculitis, vasculopathy, moya-moya with no clinical events or TIA only
Exclusion Criteria
• A patient who meets any of the following criteria will not be eligible for the study:
1. Cerebral haemorrhage not associated with ischemic infarct.
2. Hypoxic ischemic event with diffuse or bilateral infarction alone (not associated with one of the above conditions).