Coughing in Infratentorial Brain Lesion Patients


Phase N/A Results N/A

Trial Description

To record diaphragm excursion in infratentorial brain lesions patients with dysphagia during coughing and compare them to those with supratentorial brain lesion patients with dysphasia and those with no dysphagia at a university affiliated rehabilitation department.

Detailed Description

Our previous work has shown that stroke patients with dysphagia have impaired diaphragm excursion in comparison to those with no dysphagia. It has been postulated that respiratory and cough function are primarily controlled by respiratory and swallowing centers located in the brainstem.We postulated that those with infratentorial brain lesions would have more impaired cough and respiratory function than those with non-brainstem lesions and supratentorial brain lesions.
However there has been no studies whether those with infratentorial brain lesions have more impaired cough function and decreased diaphragm excursion than those with supratentorial brain lesions.



  • Not applicable (observational study with no active intervention) Other
    Intervention Desc: Not applicable
    ARM 1: Kind: Experimental
    Label: Brainstem dysphagia patients
    Description: Brainstem patients with confirmed evidence of dysphagia
    ARM 2: Kind: Experimental
    Label: Non brainstem dysphagia patients
    Description: Non brainstem patients with confirmed evidence of dysphagia
    ARM 3: Kind: Experimental
    Label: Brain lesion patients without dysphagia
    Description: Brain lesion patients with no evidence of dysphagia

Trial Design

  • Observation: Cohort
  • Perspective: Cross-Sectional
  • Sampling: Probability Sample

Trial Population

Dysphagia patients due to brain lesions at a university affiliated hospital


Type Measure Time Frame Safety Issue
Primary Diaphragm excursion baseline one time No
Secondary Maximal inspiratory pressure baseline one time No
Secondary Peak cough flow force during voluntary coughing baseline one time No