Correlation Analysis Between Brain Lesions and Sensorimotor Impairments in Individuals With Stroke (Preliminary Study)

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Inclusion criteria for healthy subjects are:
- medically stable;
- 18 - 99 years of age;
- able to hear the instructions given during the study
Inclusion criteria for stroke patients are:
- at least 6 months post-stroke;
- medically stable;
- 18 - 99 years of age;
- subcortical or cortical infarct confirmed with MRI;
- Mini-mental State Exam > 24/30 (Folstein et al., 1975);
- able to hear the instructions given during the study;
- able to comprehend the instructions given during the study;
- able to commit time to participate in a 6-12-weeks rehabilitation program

Exclusion Criteria

Exclusion criteria for healthy subjects are:
- having ever experienced a stroke or another brain injury or illness related to the brain that has lasting effects or effects experienced at the moment of recruitment;
- severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
- contractures in tested arm that hinder persons from keeping the outstretched arm in a relaxed position;
- interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
- exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
- pregnant or nursing mother;
- adults lacking capacity to consent
Exclusion criteria for stroke patients are:
- insular or cerebellar infarcts/brain lesions;
- unilateral spatial neglect, identified by a standard neuropsychological assessment (Bell's test (score/35, Gauthier et al., 1989);
- aphasia;
- apraxia (TULIA, Vanbellingen et al., 2011);
- severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
- contractures in the hemiplegic arm that hinder patients from keeping the outstretched arm in a relaxed position;
- interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
- patients currently receiving therapy for their hemiplegic arm, the latter in order to avoid confounding treatment effects;
- exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
- pregnant or nursing mother;
- adults lacking capacity to consent