10 patients received hypothermia, while 9 were normothermic controls. It took an average of 3.5 hours to reach the target temperature of 32º C. In 9 out of 10 patients, the target was overshot, and the entire cooling and rewarming process lasted an average of 47.4 hours. There was a measurable, but non-statistically significant trend (P = 0.14) towards better clinical outcome in the hypothermic group: 50% of the hypothermic patients and 90% of the normothermic patients had bad outcomes. There was also a trend towards reduced infarct volume in the hypothermic cohort. Sinus bradycardia was the only complication to occur with a significantly higher frequency in the hypothermia group than in the control group. Researchers conclude that induced moderate hypothermia in acute ischemic stroke is both feasible and safe. A larger study of poststroke cooling is underway.