Contrast Enhanced Ultrasound of Carotid Plaque in Acute Ischemic Stroke "CUSCAS"


Phase N/A Results N/A

Trial Description

This is a biomedical, single-center, and prospective study of a consecutive patients cohort in acute ischemic stroke with carotid plaque.

Detailed Description

The main objective of this study is to evaluate the prevalence of the contrast taking carotid plaques in these acute ischemic strokes.
The secondary objectives are:
- to determine the clinical, sonographic, CT scanner and MRI characteristics of patients in constituted acute cerebral ischemia with carotid atherosclerotic plaque taking contrast to the doppler ultrasound.
- to explore of the plaque contrast enhancement at 6 months (new injection).



  • Contrast injection Sonovue® Other
    Intervention Desc: In addition to standardized assessment routine care, a contrast injection will be performed during the neck vessels doppler ultrasound.
    ARM 1: Kind: Experimental
    Label: Acute ischemic carotid stroke
    Description: Patients hospitalized in the neurovascular intensive care unit for an acute ischemic stroke with a carotid plaque responding to inclusion criteria. These patients receive a contrast injection Sonovue® will be performed during the neck vessels doppler ultrasound.


Type Measure Time Frame Safety Issue
Primary Contrast enhancement of carotid plaque prevalence in ultrasound doppler Day 1
Secondary Patient's demographics data Day 1
Secondary Patient's sonographic and MRI characteristics. Day1
Secondary describe the aspect of the carotid plaque on CT angiography. between 1 to 5 days
Secondary Persistence , decrease or loss of contrast enhancement in ultrasound doppler. Month 6
Secondary Cerebral infarction recurrence Month 6