Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- first-ever ischemic or hemorrhagic stroke at least 1 year earlier
- hand function impairment
- ability to give informed consent and comprehend instructions

Exclusion Criteria

- previous surgical intervention on vagus nerve
- low hearth rate (< 60 bpm)
- cognitive impairment or any substantial decrease in alertness, language reception, or attention that might interfere with understanding instructions for motor testing
- apraxia
- excessive pain in any joint of the paretic extremity
- advanced liver, kidney, cardiac or pulmonary disease
- history of significant alcohol or drug abuse
- depression or use of neuropsychotropic drugs such as antidepressants or benzodiazepines
- pregnant women