Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial


Phase 1/2 Results

Summary of Purpose

The purpose of this study is determine the effects of using of a combination of two drugs--integrilin (eptifibatide) and activase (recombinant tissue plasminogen activator, rt-PA, or recombinant t-PA)--to dissolve blood clots in patients who have a stroke.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 7 May 2009.

1 Jul 2003 7 Nov 2005 Unavailable 1 Jul 2007 1 May 2009 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Double-Blind
  • Purpose: Treatment


  • Pam Schmit RN, BSN Clear Trial Clinical Coordinator University of Cincinnati College of Medicine Department of Emergency Medicine Rm. 6101 MSB, Albert Sabin Way Cincinnati, Ohio 45267-0769 Phone: 513-558-6142