Clopidogrel vs. Aspirin in Patients at Risk of Ischemic Events "CAPRIE"


Phase 3 Results


Patients treated with clopidogrel had a 5.32% annual risk of ischemic stroke, myocardial infarction or vascular death whereas patients treated with aspirin had a 5.83% annual risk of the same events. These rates show a statistically significant (p=0.043) relative-risk reduction of 8.7% in favor of clopidogrel (95% CI 0.3-16.5).