Clopidogrel vs. Aspirin in Patients at Risk of Ischemic Events "CAPRIE"


Phase 3 Results

Trial Description

To test the relative efficacy of clopidogrel (75 mg once daily ) and aspirin (325 mg once daily) for prevention of stroke, myocardial infarction or vascular death.


  • Aspirin (stroke prevention) Drug
    Intervention Desc: Antiplatelet agent; inhibits thromboxane A2
  • Clopidogrel (Plavix┬«)Drug
    Other Names: Plavix, Clodelib, Clovelen
    Intervention Desc: Antiplatelet agent

Trial Design

Randomized, double-blind, international trial of 19,185 patients at 384 centers in 16 countries.


Type Measure Time Frame Safety Issue
Primary Ischemic stroke, myocardial infarction, or vascular death during 1-3 year follow-up period.