Clinical importance of microbleeds in patients receiving IV thrombolysis


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

Patients with a clinical diagnosis of ischemic stroke with an NIHSSS > 5, who could be treated with IV tPA injection within 3 to 6 hours after symptom onset.

Exclusion Criteria

Patients were comatose or severely obtunded, had rapidly improving symptoms, had a history of stroke within the last 6 weeks, had a premorbid Rankin score of 3 or higher, had a seizure at symptoms onset, had previously known intracranial hemorrhage, or had evidence of acute hemorrhage or clearly identifiable hypodensity 1/3 of the middle cerebral artery territory on baseline noncontrast brain CT.