Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS) "CLINICS"


Phase 4 Results N/A

Summary of Purpose

The main purpose of the study is to determine noninvasive markers of brain involvement in Chagas disease. In a subgroup of patients with high intensity transient signals (HITS) on transcranial Doppler monitorization, the investigators aim to determine the efficacy and safety of aspirin in preventing microembolization in patients with no previous history of stroke. Specific aims are listed bellow: (1) to...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 2 September 2015.

1 Jul 2012 24 Jul 2012 1 Sep 2016 1 Sep 2016 1 Sep 2015 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


  • Jamary Oliveira-Filho, MD, PhD