Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke "CLAST"

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Acute stroke

Inclusion Criteria

- 50-99% atherosclerotic carotid artery stenosis
- Acute atherothrombotic stroke/TIA (according to TOAST-criteria) within the first 3 days after vascular event

Exclusion Criteria

- risk factors of non-atherothrombotic stroke (according to TOAST-criteria)
- cancer
- exacerbation of decompensated chronic diseases
- infections
- acute cardiovascular diseases
- large operation during 1 month before enrollment
- Cortexin, Actovegin, Cerebrolysin, Erythropoetin administration during 1 week before enrollment.
Stable ACAS
Inclusion Criteria:
- 50-99% atherosclerotic carotid artery stenosis
- no history of vascular events during one month before enrollment
Exclusion Criteria:
- risk factors of non-atherothrombotic stroke (according to TOAST-criteria)
- cancer
- exacerbation of decompensated chronic diseases
- infections
- acute cardiovascular diseases
- large operation during 1 month before enrollment
- Cortexin, Actovegin, Cerebrolysin, Erythropoetin administration during 1 week before enrollment.
Control group
Inclusion Criteria:
- intima media thickness less then 1mm
- no history of stroke/TIAs
Exclusion Criteria:
- risk factors of non-atherothrombotic stroke (according to TOAST-criteria)
- cancer
- exacerbation of decompensated chronic diseases
- infections
- acute cardiovascular diseases
- large operation during 1 month before enrollment
- Cortexin, Actovegin, Cerebrolysin, Erythropoetin administration during 1 week before enrollment.