China Stroke Secondary Prevention Trial "CSSPT"

Withdrawn

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Patients presenting within one months of ischemic stroke (ischemic or hemorrhagic) or TIA
- Homocysteine level ≥ 15μmol/L
- Agree to take study medication;Be geographically accessible for follow-up
- Provide written informed consent

Exclusion Criteria

- Other cause of ischemic stroke (cardioembolism; stroke of other determined etiology, and stroke of undetermined etiology according to TOAST subtypes) or hemorrhagic stroke (intracranial vascular malformations; cerebral amyloid angiopathy; trauma and bleeding disorders etc)
- Use of vitamin supplements containing folate, B6 or B12
- Pregnancy or women of child-bearing potential who are at risk of pregnancy
- Limited life expectancy