China Antihypertensive Trial in Acute Ischemic Stroke "CATIS"

Active, not recruiting

Phase N/A Results

Eligibility Criteria

Inclusion Criteria

- Age ≥22 years
- Ischemic stroke onset within 48 hours confirmed by imaging (CT scan or MRI) study
- Systolic BP≥140 and <220 mm Hg and diastolic BP≥80 mm Hg
- No contraindications to antihypertensive treatment
- Able and willing to sign informed consent by patients or their direct family members

Exclusion Criteria

- Individuals with hemorrhagic stroke
- Individuals with severe heart failure (NY Heart Association class III and IV), myocardial infarction, unstable angina, aortic dissection and cerebrovascular stenosis
- Individuals in a deep coma
- Individuals with resistant hypertension [systolic BP ≥170 mm Hg despite use of 4 or more antihypertensive medications for half a year or longer]
- Intravenous thrombolytic therapy (such as intravenous rtPA)
- Individuals who are unable to participate in follow-up examination
- Current pregnant women