Cervical Artery Dissection In Stroke Study: Feasibility Phase. "CADISS "


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. Extra cranial carotid or vertebral artery dissection with symptom onset within the last 7 days. This includes: 1.1. Ipsilateral Transient Ischemic Attack (TIA) or stroke with known date of onset 1.2. Ipsilateral Horner’s syndrome or neck pain with known date of onset 2. Imaging evidence of definite or probable dissection on Magnetic Resonance Imaging (MRI)/ Magnetic Resonance Angiography (MRA), Computed Tomographic Angiography (CTA) or ultrasound (patients can be initially randomised on ultrasound alone but subsequent MR or CTA confirmation is needed)

Exclusion Criteria

1. Intracranial cerebral artery dissection 2. Symptom onset >7 days 3. Contraindications to either antiplatelet agents or anticoagulation therapy, including active peptic ulceration, bleeding peptic ulcer within 1 year 4. Patient refusal to consent 5. Patients already taking antiplatelets or anticoagulants for other reasons e.g. prosthetic heart valves in whom the treatment cannot be replaced by either antiplatelets or anticoagulants 6. Women who are pregnant