Carotid Revascularization Endarterectomy Versus Stenting Trial "CREST"

Active, not recruiting

Phase 3 Results

Summary of Purpose

The purpose of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is to compare the relatively new procedure of stent-assisted carotid angioplasty (CAS) to the traditional and accepted surgical approach of carotid endarterectomy (CEA) for the treatment of carotid artery stenosis to prevent recurrent strokes in those patients who have had a TIA (transient ischemic attack) or a mild stroke...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 4 January 2016.

1 Dec 2000 25 Feb 2000 1 Feb 2011 1 Dec 2016 1 Oct 2015 26 Sep 2013
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Prevention
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


  • Mary Longbottom, CCRP CREST Director for Data Quality Mayo Clinic Florida PH: 904-953-7742 FX: 904-953-0277