Brain Computer Interface(BCI) System for Stroke Rehabilitation

Completed

Phase N/A Results N/A

Trial Description

A BCI system for stroke subjects will be designed in an attempt to train the motor-related areas in their brains responsible for hand open/close function. A robot hand will be used and controlled by the system in real time based on EEG pattern for identification of motion intention for hand movements in the motor cortex. A randomized controlled trial study design will be adopted. All subjects will be assessed by clinical assessments including FMA and neuroimaging assessments using multimodal MR techniques before and after the training to evaluate training effectiveness.

Conditions

Interventions

  • BCI using EEG signals Procedure
    Intervention Desc: A robot hand will be used and controlled by the system in real time based on EEG pattern for identification of motion intention for hand movements in the cortex.
    ARM 1: Kind: Experimental
    Label: BCI-robot (I)
    Description: EEG guided training based on ipsilesional EEG signals; Training for 30 sessions
    ARM 2: Kind: Experimental
    Label: BCI-robot (IC)
    Description: EEG guided training based on both ipsilesional and contralesional EEG signals; Training for 30 sessions
    ARM 3: Kind: Experimental
    Label: robot
    Description: Training for 30 sessions

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary FMA-UE 3-month followup No
Secondary ARAT 3-month followup No
Secondary MAS 3-month followup No
Secondary MRI 3-month followup No

Sponsors