Brain Biomarkers of Response to Treatment for Apraxia of Speech "SPT"

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Inclusion criteria are age 40-90
- primary English speaker since < age 5
- a history of a single left hemisphere stroke
- at least 1 year post-stroke
- at least 12 years of education
- pre-morbidly right-handed (Edinburgh Handedness Questionnaire)
- within normal limits on the Test of Non-Verbal Intelligence

Exclusion Criteria

- Exclusion criteria will include a pre-morbid neurologic or psychiatric history
- history/current substance abuse disorder
- MRI contraindications
- other motor speech disorders (e.g., dysarthria)
- current or recent (<2 months) speech/language therapy
- prior SPT
- pre-morbid history of speech/language disorders
- significant hearing disabilities (based on a pure-tone audiological screen at 35 dB HL at 500, 1K, and 2K Hz for at least one ear)
- aphasia severity resulting in <30th percentile performance on the Porch Index of Communicative Ability-R