Brain and Cognitive Reserve "BCN"

Recruiting

Phase N/A Results N/A

Trial Description

Ischemic strokes are one of the leading causes of handicap and death in elderly people in France.
Cognitive reserve (CR) is an active model, defined as a function of lifetime intellectual activities and other environmental factors that explain differential susceptibility to functional impairment in the presence of pathology or other neurological insult. CR is estimated using variables for cognitive activity: years of education, professional status, socioeconomic status… Furthermore, brain reverse (BR) is a passive and quantitative model that depend on brain size and other quantitative aspects of the brain that explain differential susceptibility to functional impairment in the presence of pathology.
Firstly, volume and localization of ischemic strokes have a great impact on CR and BR due to brain injury. On the other hand, CR influences the severity and the expression of cognitive diseases.
The investigators realize a prospective study in order to assess the impact of CR and BR on cognitive prognosis after a right middle cerebral artery ischemic stroke in elderly patients.

Conditions

Interventions

  • Neurologic and neuropsychological evaluation Other
    Intervention Desc: cognitive prognosis, cognitive reserve, brain volume will be studied on patients with scale, questionnaire, magnetic resonance imaging
    ARM 1: Kind: Experimental
    Label: neurologic and neuropsychological evaluation

Trial Design

  • Masking: Open Label
  • Purpose: Basic Science
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary evaluation of cognitive prognosis one year post Ischemic stroke No
Secondary Volume of leucoencephalopathy one year post Ischemic stroke No
Secondary volume of hippocampic one year post Ischemic stroke No
Secondary brain injury one year post Ischemic stroke No
Secondary volume of ischemic stroke one year post Ischemic stroke No
Secondary evaluation of cognitive reserve one year post Ischemic stroke No

Sponsors