Botulinum Toxin Injections by Ultrasounds Guidance and Stretching Exercise in Spastic Toe Clawing

Completed

Phase 3 Results N/A

Eligibility Criteria

Inclusion Criteria

- Patient with spasticity toe clawing(metatarsophalange jointextension, proximal and distal phalange joint flexion)
- MAS scale of metatarsophalange joint and interphalangeal joint more than 2
- Pain during walking, abnormal gait patterns and can't wear shoess due to claw toe
- Haven't received botox or phenol or alcohol injections before

Exclusion Criteria

- Lower extremities joint contrature, bone deformity
- Had received botox injections or phenol injections or before due to lower extremities spasticity
- Combine other neuromuscular system disease
- Severe cognition disorder or aphasia after stroke
- Significant atrophy of flexor digitorum longus and brevis
- Allergy to botox
- Infection on injection site
- Have systemic infection
- Now accept aminioglycoside or other medicine will affect neuromusclar transition