To assess the efficacy of botulinum toxin A (Dysport) in conjunction with functional electrical stimulation (FES) and physical therapy, in restoring normal gait to post-stroke patients with spastic foot drop.
- Botulinum toxin (Dysport)Drug
Intervention Desc: Antispasticity agent.
- Physical therapy Other
- Electrical stimulation Other
Intervention Desc: This category includes any form of electrical stimulation intended to improve motor function or pain after stroke.
Multicenter, randomized, controlled study
Patients in both the control and treatment groups underwent a 4-week assessment period, and received physical therapy throughout the trial. The treatment group also received FES stimulation of the peroneal nerve and 800 U injections of botulinum toxin A delivered to the triceps surae under EMG guidance.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Mean walking speed|
|Secondary||Physiological Cost Index, Rivermead Motor Assessment Scale, Modified Ashworth, Barthel Index, and SF 36 Health Survey scores were recorded, as well as clonus and the patients' reflexes. Semi-structured interviews were also performed.|