Blood Pressure Target in Acute Stroke to Reduce hemorrhaGe After Endovascular Therapy "BP-TARGET"

Recruiting

Phase N/A Results N/A

Update History

1 Sep '17
Trial name was updated.
New
Blood Pressure Target in Acute Stroke to Reduce hemorrhaGe After Endovascular Therapy
28 Jul '17
The Summary of Purpose was updated.
New
A randomized, multicenter study comparing two strategies: 1 / standard management of systolic blood pressure according to international recommendations (systolic blood pressure <185 mm Hg) versus 2 / intensive blood pressure management Systolic with a target <130 mm Hg.
Old
A randomized, multicenter study comparing two strategies: 1 / standard management of systolic blood pressure according to international recommendations (systolic blood pressure <185 mm Hg) versus 2 / intensive blood pressure management Systolic with a target <130 mm Hg.
The description was updated.
New
Patients will be followed for 3 months: - inclusion after reperfusion: clinical evaluation with NIHSS (National Institute of Health Stroke Score) score, measurement of blood pressure. - within 24 hours after reperfusion: blood pressure measurements - at 24 hours: measurement of blood pressure (T0 + 24 h and evaluation of the NIHSS score. - Between 24 and 36 hours :cerebral scan (assessment of hemorrhagic transformations and cerebral infarction volumes). For some centers: Cerebral MRI without injection between H24 and H36 - 72 hours after reperfusion: Cerebral scanner in case of hyperdensity on the initial scanner - 3 months after reperfusion: disability assessment by Rankin score
Old
Patients will be followed for 3 months: - inclusion after reperfusion: clinical evaluation with NIHSS (National Institute of Health Stroke Score) score, measurement of blood pressure. - within 24 hours after reperfusion: blood pressure measurements - at 24 hours: measurement of blood pressure (T0 + 24 h and evaluation of the NIHSS score. - Between 24 and 36 hours :cerebral scan (assessment of hemorrhagic transformations and cerebral infarction volumes). For some centers: Cerebral MRI without injection between H24 and H36 - 72 hours after reperfusion: Cerebral scanner in case of hyperdensity on the initial scanner - 3 months after reperfusion: disability assessment by Rankin score
The eligibility criteria were updated.
New
Inclusion Criteria: - Occlusion of internal carotid arteries, proximal middle cerebral (segment M1). - Reperfusion after a thrombectomy procedure (defined by a 2b-3 TICI score -Thrombolysis In Cerebral Infarction- score). Exclusion Criteria: - Per-procedure hemorrhagic complications (prior to reperfusion) - Systolic blood pressure at baseline <130 mm Hg - Pre-existing stroke handicap defined by a Rankin score (modified scale, mRS)> 3 - Known pregnancy - Legal protection - Non-affiliation to a social security scheme - Refusal of the patient (or of his / her relatives in case of urgent inclusion)
Old
Inclusion Criteria: - Occlusion of internal carotid arteries, proximal middle cerebral (segment M1). - Reperfusion after a thrombectomy procedure (defined by a 2b-3 TICI score -Thrombolysis In Cerebral Infarction- score). Exclusion Criteria: - Per-procedure hemorrhagic complications (prior to reperfusion) - Systolic blood pressure at baseline <130 mm Hg - Pre-existing stroke handicap defined by a Rankin score (modified scale, mRS)> 3 - Known pregnancy - Legal protection - Non-affiliation to a social security scheme - Refusal of the patient (or of his / her relatives in case of urgent inclusion)
A location was updated in Paris.
New
The overall status was updated to "Recruiting" at Fondation Ophtalmologique A de Rothschild.