A randomized, multicenter study comparing two strategies: 1 / standard management of systolic blood pressure according to international recommendations (systolic blood pressure <185 mm Hg) versus 2 / intensive blood pressure management Systolic with a target <130 mm Hg.
Patients will be followed for 3 months:
- inclusion after reperfusion: clinical evaluation with NIHSS (National Institute of Health Stroke Score) score, measurement of blood pressure.
- within 24 hours after reperfusion: blood pressure measurements
- at 24 hours: measurement of blood pressure (T0 + 24 h and evaluation of the NIHSS score.
- Between 24 and 36 hours :cerebral scan (assessment of hemorrhagic transformations and cerebral infarction volumes). For some centers: Cerebral MRI without injection between H24 and H36
- 72 hours after reperfusion: Cerebral scanner in case of hyperdensity on the initial scanner
- 3 months after reperfusion: disability assessment by Rankin score
- Systolic blood pressure target < 130 mm Hg Other
Intervention Desc: Adaptation of antihypertensive treatments to reach the Systolic blood pressure target < 130 mm Hg ARM 1: Kind: Experimental Label: Intensive blood pressure management
- Systolic blood pressure target < 185 mm Hg Other
Intervention Desc: Adaptation of antihypertensive treatments to reach the Systolic blood pressure target < 185 mm Hg ARM 1: Kind: Experimental Label: Standard blood pressure management
|Type||Measure||Time Frame||Safety Issue|
|Primary||Rate of patients with intracranial hemorrhagic complications||Scan performed between 24 and 36 hours after thrombectomy|