Blood Pressure Reduction to Limit the Evolution of Vascular Brain Lesions in Elderly Individuals "LEOPOLD"


Phase 4 Results N/A

Summary of Purpose

The purpose of the study is to test the hypothesis of slowing the progression of White Matter Lesions (WML) by lowering blood pressure (BP) in patients with cognitive complaints and a moderate to high grade of WML on brain MRI.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 30 June 2016.

1 Sep 2015 27 Apr 2015 1 Jan 2019 1 Jan 2019 1 Jun 2016 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Prevention
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment