Autologous Cell Therapy After Stroke

Withdrawn

Phase 1 Results N/A

Eligibility Criteria

Inclusion Criteria

- Ischemic stroke that is supratentorial in location and < 72 hours old between stroke onset and bone marrow aspiration
- No major pre-stroke disability
- NIH stroke scale score of 7-24
- Able to undergo bedside bone marrow aspiration
- Age 18-85 years, inclusive
- Reasonable likelihood of receiving standard physical, occupational and speech rehabilitation therapy

Exclusion Criteria

- No major active hematological, immunological, or oncological diagnoses
- Pregnancy
- Lactating mothers
- At least 24 hours time of any thrombolytic therapy and time of bone marrow aspiration
- Allergy to penicillin or to fetal bovine serum
- Active, major co-existent neurological or psychiatric disease
- Infection with HIV, hepatitis B or C, or syphilis
- Any diagnosis that makes survival to 90 days post-stroke unlikely
- Participation in an experimental therapeutic clinical trial in the prior three months