Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke Patients
Completed
Phase 1/2 Results N/AEligibility Criteria
Inclusion Criteria
- Patients with cerebral embolism.- NIHSS score is more than (or equal to) 10.
- On day 7 after onset of stroke, the improvement of NIHSS is less than (or equal to) 5, compared with the level at administration.
- Bone marrow aspiration can be done in 10 days after onset of stroke
Exclusion Criteria
- Patient with cerebral hemorrhage or symptomatic hemorrhagic infarction.- Patient who expects brain surgery.
- Patient with acute myocardial infarction.
- Patient with coagulation disorder.
- Number of Platelet < 100000/mm3
- Serum creatinine level >2.0mg/dl
- Patient with malignancy.
- Patient with uncontrolled proliferative diabetic retinopathy.
- Patient suspected infective endocarditis.
- HBV, HCV, HIV or HTLV positive
View Trial Locations
Recruitment
- Enrollment: 12
- Gender: Both
- Minimum Age: 20 Years
- Accepts Healthy Volunteers: No
- 1 location, 1 country
Principal Investigator
- Akihiko Taguchi, MD.PhD
Department of Cerebrovascular Disease, National Cardiovascular Center