Atlantic Canada Modified Constraint Induced Movement Therapy Trial


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. first symptomatic stroke (either ischemic or hemorrhagic) resulting in upper limb hemiparesis
2. the ability to perform a two-step command
3. age ≥ 18 years
4. residence within a 75 km radius of the Queen Elizabeth II Health Sciences Centre
5. with regard to the affected upper limb, subjects will meet standard criteria for modified constraint induced movement therapy (mCIMT) including at least 10 degrees of active wrist extension, at least 10 degrees of thumb abduction/extension, and at least 10 degrees of extension in two additional digits, repeated three times in one minute

Exclusion Criteria

1. have excessive pain in the affected upper limb (defined as > 4 on a 10 centimeter visual analog scale)
2. presence of dementia or aphasia as defined by a score of < 26 on the Montreal Cognitive Assessment
3. have a diagnosis of pre-stroke dementia
4. have a terminal illness, life-threatening co-morbidity or concomitant neurological or psychiatric illness
5. excessive tone in the upper limb (> 3 on the modified Ashworth Scale)
6. Motor Activity Log score > 2.5 (amount of use sub-scale)