Asymptomatic Carotid Surgery Trial "ACST"


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

Patients with unilateral or bilateral carotid stenosis considered appropriate for surgery, who have experienced no ipsilateral transient ischemic attack (TIA), amaurosis fugax, or stroke within the past 6 months, who have no history of ipsilateral disabling stroke or severe contralateral stroke, and who have no clear indication or contraindication for CEA, will be eligible for this trial.

Exclusion Criteria

Patients whose carotid plaques are smooth, calcified, and not significantly stenotic, who have a severe, life-threatening comorbidity other than stroke, who have recent acute myocardial infarction (MI), intracerebral neoplasia, intracerebral aneurysm, or whose carotid arteries are restenosed following a previous CEA, will be excluded from this trial.