To determine whether the addition of carotid endarterectomy to aggressive medical management can reduce the incidence of cerebral infarction in patients with asymptomatic carotid artery stenosis.
- Endarterectomy, carotid (CEA)Procedure/Surgery
Intervention Desc: Surgical therapy to remove atherosclerotic plaque in narrowed carotid arteries.
Prospective, randomized, multicenter trial of 1662 patients at 39 centers.
Daily aspirin administration and medical risk factor management for all patients, carotid endarterectomy for patients randomized to receive surgery. Patients were followed for
|Type||Measure||Time Frame||Safety Issue|
|Primary||Cerebral infarction occurring in the distribution of the study artery or any stroke or death occurring the perioperative period.|