Association Between Brain Stimulations for the Rehabilitation of Chronic Stroke Patients

Recruiting

Phase N/A Results N/A

Trial Description

Cerebrovascular accident (CVA) is a cerebrovascular disease with high incidence and morbidity in the Brazilian population, and is considered a major cause of disability in adults. Brain damage caused by stroke generates a maladaptive pattern of neural activity and modulation between the cerebral hemispheres, unbalancing in the inter-hemispheric inhibition. This condition affects patient's functional recovery.
The aim of this study is to verify the effectiveness of repetitive transcranial magnetic stimulation Association (rTMS) in the cortex motor contralesional, Transcranial Direct Current Stimulation (tDCS) in the motor cortex ipsilesional and the association between these two types of brain stimulations on the upper limb recovery after stroke.

Conditions

Interventions

  • TDCS Device
    Intervention Desc: Transcranial direct current stimulation (tDCS)
    ARM 1: Kind: Experimental
    Label: tDCS
    Description: Patients who will be treated with Transcranial direct-current stimulation (tDCS) in the ipsilesional motor cortex.
  • TMS Device
    Intervention Desc: Transcranial magnetic stimulation
    ARM 1: Kind: Experimental
    Label: rTMS
    Description: Patients who will be treated with Magnetic brain stimulation (rTMS) in the contralesional motor cortex.
  • TDCS + TMS Device
    Intervention Desc: Association between tDCS and TMS.
    ARM 1: Kind: Experimental
    Label: tDCS + rTMS
    Description: Patients who will be treated with the association between Transcranial direct-current stimulation (tDCS) and magnetic brain stimulation (rTMS), in the ipsilesional and contralesional motor cortex, respectively.

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Investigator)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Motor Function by means of the Wolf Motor Function Test change from pre to post (at least 10 days) No
Secondary Grip strength via hand dynamometer change from pre to post (at least 10 days) No
Secondary Manual Dexterity by means of the Box and Block Test change from pre to post (at least 10 days) No
Secondary Quality of Life by means of the Stroke Impact Scale change from pre to post (at least 10 days) No

Sponsors