Aspirin in Transient Ischemic Attacks "AITIA"

Completed

Phase N/A Results

Results

Analysis of the 189 patients who had not undergone carotid surgery prior to randomization revealed no difference in the cumulative probabilities of mortality, cerebral infarction and retinal infarction between the two treatment groups (p=0.18). When cases with insufficient follow-up were excluded and the number of TIAs pre and post-randomization were compared, there was a significant differential in favor of aspirin (p=0.04). Analysis of the 128 patients in the surgical group did not reveal a significant difference in the cumulative probabilities of mortality, cerebral infarction and retinal infarction. Life table analyses that eliminated non stroke-related deaths revealed a significant difference in favor of aspirin.