Aspirin and sulfinpyrazone in threatened stroke


Phase N/A Results


Aspirin reduced the risk of continuing ischemic attacks, stroke or death by 19% (P < 0.05) and also reduced risk of stroke or death by 31% (P < 0.05). Effect was sex-dependent: among men, the risk reduction for stroke or death was 48% (P < 0.005), whereas no significant trend was observed among women. For sulfinpyrazone, no risk reduction of ischemic attacks was observed, and the 10% risk reduction of stroke or death was not statistically significant. No overall synergism or antagonism was observed between the two drugs.