Anti-MAG First Administration to Human


Phase 1 Results N/A

Summary of Purpose

GSK249320 is a monoclonal antibody directed against myelin associated glycoprotein (MAG), a protein that inhibits axonal regeneration. GSK249320 acts as a MAG antagonist, and through this activity it is hypothesised that it will enhance recovery from neuronal degeneration following acute axonal injury, which occurs in spinal cord injury or stroke.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 19 July 2017.

1 Aug 2007 13 Feb 2008 9 Apr 2009 9 Apr 2009 1 Jul 2017 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Subject)
  • Purpose: Treatment
  • Endpoint: Safety Study
  • Intervention: Parallel Assignment


Not available