Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline


Phase 4 Results N/A

Eligibility Criteria

Inclusion Criteria

- Patients with essential hypertension (systolic blood pressure>=140 mmHg and/or diastolic blood pressure>=90, or treated with antihypertensive drugs)
- Patients with any finding of stroke, silent brain infarction, and white matter lesion on magnetic resonance imaging

Exclusion Criteria

- Secondary hypertension
- Atrial fibrillation
- History or signs of cerebral disorders other than cerebrovascular disease
- Malignant tumor
- Chronic renal failure
- Severe congestive heart failure
- Hyperkalemia
- Stenosis of bilateral renal artery