American Nimodipine Study "ANS"


Phase 3 Results

Eligibility Criteria

Inclusion Criteria

Stroke due to infarction as inferred by initial computed tomographic scan findings. Must present within 48 hours of onset, 21-89 years of age, reliable time of onset fixed by history or direct observation.

Exclusion Criteria

Coma, intracranial hemorrhage, tumor, infection, trauma, serious organic brain disease other than ischemic cerebral infarction as defined by entry CT scan, need for mechanical ventilation, current use of calcium antagonist therapy, pregnancy, hypotension, bradycardia, second or third-degree heart block if the patient did not have a pacemaker, severe hepatic or renal dysfunction, congestive heart failure or pneumonia.