Alternative strategies for stroke care

Completed

Phase N/A Results

Trial Description

To compare the outcomes of stroke unit care, stroke team care, and domiciliary care in acute stroke patients.

Interventions

Trial Design

Single-blind, randomized, controlled trial.

Patient Involvement

Prior to enrollment, patients underwent a thorough assessment by a stroke physician, evaluating comorbidities, premorbid function, stroke subtype, Orgogozo scale, Orpington prognostic scale, and Barthel Index scores, hematological and blood chemistry panels, and chest X-ray. Eligible patients were randomized within 72 hours of symptom onset to receive stroke unit care, stroke-team-supported care on the general wards, or domiciliary care. Patients receiving domiciliary care were admitted to a stroke unit if their status deteriorated to an extent that home care was no longer possible. Patients were followed up for one year, with outcome assessments performed at 3, 6, and 12 months.

Outcomes

Type Measure Time Frame Safety Issue
Primary Combined incidence of death and institutionalization at 1 year.
Secondary Dichotomized Rankin scale (0 - 3 = favorable outcome; 4 - 6 = unfavorable outcome) and Barthel Index (15 - 20 criteria, or 60 - 100 points = favorable outcome; 0 - 14 criteria, or 0 - 56 points = unfavorable outcome) scores

Sponsors

NHS R&D Executive's Health Technology Assessment Programme, Bromley Health Authority