Aliskiren Effect on Aortic Plaque Progression "ALPINE"

Terminated

Phase 2/3 Results

Summary of Purpose

This study is being done to assess the effectiveness of short term (~9 months) Aliskiren/Placebo therapy to slow down the progression of atherosclerotic disease in thoracic and abdominal aorta. This will be checked by comparing before and after therapy magnetic resonance imaging (MRI) pictures of the aortic wall.... Trial Stopped: Safety concerns with approved medication identified in an unrelated trial

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 9 May 2017.

1 Oct 2009 8 Aug 2011 1 Dec 2011 1 Jan 2012 1 May 2017 29 Oct 2012
Start Date First Received 1st Completion Completion Verification Results

Trial Basics

Interventions

Conditions

Sponsors

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Contacts

Not available