ADAPT A Direct Aspiration, First Pass Technique for the Endovascular Treatment of Stroke

Completed

Phase N/A Results N/A

Trial Description

In collaboration with the Neurointerventional programs at state university of new york Buffalo, state university of new york Stonybrook, Swedish Medical Center, Erlanger Health System, Vanderbilt University, and West Virginia University School of Medicine, the investigators aim to prospectively collect experiences where direct aspiration as a first pass technique is used for thrombectomy procedures.
The investigators also want to compare specific characteristics from these cases to other stroke cases where traditional thrombectomy devices were used.

Detailed Description

Traditionally, at a physician's discretion, first pass attempts at thrombectomy procedures are performed with any number of FDA cleared catheters, guide wires, and devices designed for efficient removal of clot within an intracranial vessel. Among institutions involved in this case study, the latest devices are readily available and fully support standard treatment paradigms.
However, several cases, recently completed, using only large bore catheter and aspiration have anecdotally demonstrated a superior ability to remove clot from vessels, restoring blood flow to the affected vessel and brain tissue. In these limited number of cases, full restoration of blood flow has been achieved. While this combination of approved devices is minimalistic, the efficiency of the procedure, rapid technical success, and relative simplicity of the approach is unique and should be thoroughly reviewed and possibly prepared for publication.

Conditions

Trial Design

  • Observation: Case-Only
  • Perspective: Retrospective
  • Sampling: Non-Probability Sample

Trial Population

This is a chart review of clinical data for patients who have been treated for stroke with either direct aspiration or stent retrievers. This review will be conducted at MUSC and SUNY Buffalo, SUNY Stonybrook, Swedish Medical Center, Vanderbilt University, Erlanger Health System, and West Virginia University School of Medicine. Each participating group will submit for approval at their individual institution.

Outcomes

Type Measure Time Frame Safety Issue
Primary Discharge national institutes of health stroke scale (NIHSS) approximately 7 days after index stroke No
Secondary 90 day modified Rankin Score (mRS) 90 days after procedure No

Sponsors