Acute Candesartan Cilexetil Outcomes Stroke Trial (ACCOST)

Active, not recruiting

Phase 4 Results N/A

Eligibility Criteria

Inclusion Criteria

- Acute ischaemic stroke <72 hours from symptom onset (CT proven)
- Medically stable with no evidence of acute infection and not receiving antibiotic therapy
- Neurologically stable (no progression on NIHSS)
- Able to swallow unthickened fluids safely
- Mean BP (blood pressure) >120/70 in unaffected arm

Exclusion Criteria

- Previous severe disability (Modified Rankin Score >2)
- Nursing home residents
- Previous history of congestive heart failure requiring treatment with ACE-Inhibitors or angiotensin receptor blockers
- Renal impairment (creatinine >200 mcgmol/L)
- Women of child bearing potential
- Minors <18 years of age
- History of dementia without ability to consent